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1

Protein Sensors for Membrane Sterols

Joseph L. Goldstein, Russell A. DeBose-Boyd, Michael S. Brown

Journal:

Year:

2006

Language:

english

File:

PDF, 1.18 MB

english, 2006

2

Synergistic Impact of d -δ-Tocotrienol and Geranylgeraniol on the Growth and HMG CoA Reductase of Human DU145 Prostate Carcinoma Cells

Yeganehjoo, Hoda, DeBose-Boyd, Russell, McFarlin, Brian K., Mo, Huanbiao

Journal:

Nutrition and Cancer

Year:

2017

Language:

english

File:

PDF, 780 KB

english, 2017

3

Feedback regulation of cholesterol synthesis: sterol-accelerated ubiquitination and degradation of HMG CoA reductase

DeBose-Boyd, Russell A

Journal:

Year:

2008

Language:

english

File:

PDF, 830 KB

english, 2008

4

Uncoupling hypoxia signaling from oxygen sensing in the liver results in hypoketotic hypoglycemic death

Kucejova, B, Sunny, N E, Nguyen, A D, Hallac, R, Fu, X, Peña-Llopis, S, Mason, R P, DeBerardinis, R J, Xie, X-J, DeBose-Boyd, R

Journal:

Year:

2011

Language:

english

File:

PDF, 1.12 MB

english, 2011

5

The ruminant parasite Haemonchus contortus expresses an α1,3-fucosyltransferase capable of synthesizing the Lewis x and sialyl Lewis x antigens

Russell A DeBose-Boyd, A. Kwame Nyame, Douglas P Jasmer, Richard D Cummings

Journal:

Glycoconjugate Journal

Year:

1998

Language:

english

File:

PDF, 1.51 MB

english, 1998

6

Schistosoma mansoni:Characterization of an α1–3 Fucosyltransferase in Adult Parasites

Russell DeBose-Boyd, A.Kwame Nyame, Richard D. Cummings

Journal:

Experimental Parasitology

Year:

1996

Language:

english

File:

PDF, 153 KB

english, 1996

7

α1,4-Fucosyltransferase Activity in Human Serum and Saliva

Russell A. Debose-Boyd, A.Kwame Nyame, David F. Smith, Richard D. Cummings

Journal:

Archives of Biochemistry and Biophysics

Year:

1996

Language:

english

File:

PDF, 167 KB

english, 1996

8

Insig-mediated degradation of HMG CoA reductase stimulated by lanosterol, an intermediate in the synthesis of cholesterol

Bao-Liang Song, Norman B. Javitt, Russell A. DeBose-Boyd

Journal:

Cell Metabolism

Year:

2005

Language:

english

File:

PDF, 647 KB

english, 2005

9

A Helping Hand for Cytochrome P450 Enzymes

Russell A. DeBose-Boyd

Journal:

Cell Metabolism

Year:

2007

Language:

english

File:

PDF, 228 KB

english, 2007

10

Ufd1 Is a Cofactor of gp78 and Plays a Key Role in Cholesterol Metabolism by Regulating the Stability of HMG-CoA Reductase

Jian Cao, Jiang Wang, Wei Qi, Hong-Hua Miao, Jing Wang, Liang Ge, Russell A. DeBose-Boyd, Jing-Jie Tang, Bo-Liang Li, Bao-Liang Song

Journal:

Cell Metabolism

Year:

2007

Language:

english

File:

PDF, 1.50 MB

english, 2007

11

Knowing When to Let Go: Endosomal Release of LDL from the LDL-Receptor

Russell A. DeBose-Boyd

Journal:

Year:

2004

Language:

english

File:

PDF, 73 KB

english, 2004

12

Gp78, a Membrane-Anchored Ubiquitin Ligase, Associates with Insig-1 and Couples Sterol-Regulated Ubiquitination to Degradation of HMG CoA Reductase

Bao-Liang Song, Navdar Sever, Russell A. DeBose-Boyd

Journal:

Year:

2005

Language:

english

File:

PDF, 792 KB

english, 2005

13

Transport-Dependent Proteolysis of SREBP: Relocation of Site-1 Protease from Golgi to ER Obviates the Need for SREBP Transport to Golgi

Russell A DeBose-Boyd, Michael S Brown, Wei-Ping Li, Axel Nohturfft, Joseph L Goldstein, Peter J Espenshade

Journal:

Year:

1999

Language:

english

File:

PDF, 385 KB

english, 1999

14

Accelerated Degradation of HMG CoA Reductase Mediated by Binding of Insig-1 to Its Sterol-Sensing Domain

Navdar Sever, Tong Yang, Michael S Brown, Joseph L Goldstein, Russell A DeBose-Boyd

Journal:

Year:

2003

Language:

english

File:

PDF, 354 KB

english, 2003

15

Geranylgeraniol suppresses the viability of human DU145 prostate carcinoma cells and the level of HMG CoA reductase

Fernandes, N. V., Yeganehjoo, H., Katuru, R., DeBose-Boyd, R. A., Morris, L. L., Michon, R., Yu, Z.-L., Mo, H.

Journal:

Experimental Biology and Medicine

Year:

2013

Language:

english

File:

PDF, 590 KB

english, 2013

16

Sterols Regulate Cycling of SREBP Cleavage-Activating Protein (SCAP) between Endoplasmic Reticulum and Golgi

Axel Nohturfft, Russell A. DeBose-Boyd, Sigrid Scheek, Joseph L. Goldstein and Michael S. Brown

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.64 MB

english, 1999

17

Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8

Youngah Jo, Peter C. W. Lee, Peter V. Sguigna and Russell A. DeBose-Boyd

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.76 MB

english, 2011

18

Regulation of Cholesterol and Fatty Acid Synthesis

Ye, J., DeBose-Boyd, R. A.

Journal:

Cold Spring Harbor Perspectives in Biology

Year:

2011

Language:

english

File:

PDF, 687 KB

english, 2011

19

Insig-dependent Ubiquitination and Degradation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Stimulated by - and -Tocotrienols

Song, B.-L., DeBose-Boyd, R. A.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 1.09 MB

english, 2006

20

Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi

Nohturfft, A., DeBose-Boyd, R. A., Scheek, S., Goldstein, J. L., Brown, M. S.

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 223 KB

english, 1999

21

Insig-dependent Ubiquitination and Degradation of Mammalian 3-Hydroxy-3-methylglutaryl-CoA Reductase Stimulated by Sterols and Geranylgeraniol

Sever, N., Song, B.-L., Yabe, D., Goldstein, J. L., Brown, M. S., DeBose-Boyd, R. A.

Journal:

Journal of Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 1.11 MB

english, 2003

22

Sterol-induced Dislocation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase from Endoplasmic Reticulum Membranes into the Cytosol through a Subcellular Compartment Resembling Lipid Droplets

Hartman, I. Z., Liu, P., Zehmer, J. K., Luby-Phelps, K., Jo, Y., Anderson, R. G. W., DeBose-Boyd, R. A.

Journal:

Journal of Biological Chemistry

Year:

2010

Language:

english

File:

PDF, 2.45 MB

english, 2010

23

Sequential Actions of the AAA-ATPase Valosin-containing Protein (VCP)/p97 and the Proteasome 19 S Regulatory Particle in Sterol-accelerated, Endoplasmic Reticulum (ER)-associated Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase

Morris, L. L., Hartman, I. Z., Jun, D.-J., Seemann, J., DeBose-Boyd, R. A.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.64 MB

english, 2014

24

Membrane-associated Ubiquitin Ligase Complex Containing gp78 Mediates Sterol-accelerated Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase

Jo, Y., Sguigna, P. V., DeBose-Boyd, R. A.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 1.95 MB

english, 2011

25

Failure to Cleave Sterol Regulatory Element-binding Proteins (SREBPs) Causes Cholesterol Auxotrophy in Chinese Hamster Ovary Cells with Genetic Absence of SREBP Cleavage-activating Protein

Rawson, R. B., DeBose-Boyd, R., Goldstein, J. L., Brown, M. S.

Journal:

Journal of Biological Chemistry

Year:

1999

Language:

english

File:

PDF, 448 KB

english, 1999

26

Ubiquitination of 3-Hydroxy-3-methylglutaryl-CoA Reductase in Permeabilized Cells Mediated by Cytosolic E1 and a Putative Membrane-bound Ubiquitin Ligase

Song, B.-L., DeBose-Boyd, R. A.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 425 KB

english, 2004

27

Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8

Jo, Y., Lee, P. C. W., Sguigna, P. V., DeBose-Boyd, R. A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.00 MB

english, 2011

28

Sufficient production of geranylgeraniol is required to maintain endotoxin tolerance in macrophages

Kim, J., Lee, J. N., Ye, J., Hao, R., DeBose-Boyd, R., Ye, J.

Journal:

The Journal of Lipid Research

Year:

2013

Language:

english

File:

PDF, 1009 KB

english, 2013

29

Mutations within the membrane domain of HMG-CoA reductase confer resistance to sterol-accelerated degradation

Lee, P. C. W., Nguyen, A. D., DeBose-Boyd, R. A.

Journal:

The Journal of Lipid Research

Year:

2006

Language:

english

File:

PDF, 641 KB

english, 2006

30

Hypoxia Stimulates Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase through Accumulation of Lanosterol and Hypoxia-Inducible Factor-mediated Induction of Insigs

Nguyen, A. D., McDonald, J. G., Bruick, R. K., DeBose-Boyd, R. A.

Journal:

Journal of Biological Chemistry

Year:

2007

Language:

english

File:

PDF, 1.47 MB

english, 2007

31

Intramembrane glycine mediates multimerization of Insig-2, a requirement for sterol regulation in Chinese hamster ovary cells

Lee, P. C. W., DeBose-Boyd, R. A.

Journal:

The Journal of Lipid Research

Year:

2010

Language:

english

File:

PDF, 1.50 MB

english, 2010

32

Insig-mediated, Sterol-accelerated Degradation of the Membrane Domain of Hamster 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase in Insect Cells

Nguyen, A. D., Lee, S. H., DeBose-Boyd, R. A.

Journal:

Journal of Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 2.04 MB

english, 2009

33

Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet-associated endoplasmic reticulum membranes

Jo, Y., Hartman, I. Z., DeBose-Boyd, R. A.

Journal:

Molecular Biology of the Cell

Year:

2013

Language:

english

File:

PDF, 3.60 MB

english, 2013

34

Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR

Ou, J., Tu, H., Shan, B., Luk, A., DeBose-Boyd, R. A., Bashmakov, Y., Goldstein, J. L., Brown, M. S.

Journal:

Proceedings of the National Academy of Sciences

Year:

2001

Language:

english

File:

PDF, 338 KB

english, 2001

35

Expression of sterol regulatory element-binding protein 1c (SREBP-1c) mRNA in rat hepatoma cells requires endogenous LXR ligands

DeBose-Boyd, R. A., Ou, J., Goldstein, J. L., Brown, M. S.

Journal:

Proceedings of the National Academy of Sciences

Year:

2001

Language:

english

File:

PDF, 276 KB

english, 2001

36

Isolation of Mutant Cells Lacking Insig-1 through Selection with SR-12813, an Agent That Stimulates Degradation of 3-Hydroxy-3-methylglutaryl-Coenzyme A Reductase

Sever, N., Lee, P. C. W., Song, B.-L., Rawson, R. B., DeBose-Boyd, R. A.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 1.10 MB

english, 2004

37

Sterol-regulated Degradation of Insig-1 Mediated by the Membrane-bound Ubiquitin Ligase gp78

Lee, J. N., Song, B., DeBose-Boyd, R. A., Ye, J.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 1.04 MB

english, 2006

38

Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductase

Jo, Youngah, DeBose-Boyd, Russell A.

Journal:

Critical Reviews in Biochemistry and Molecular Biology

Year:

2010

Language:

english

File:

PDF, 1023 KB

english, 2010

39

Amplification of the gene for SCAP, coupled with Insig-1 deficiency, confers sterol resistance in mutant Chinese hamster ovary cells

Lee, P. C. W., Liu, P., Li, W.-P., DeBose-Boyd, R. A.

Journal:

The Journal of Lipid Research

Year:

2007

Language:

english

File:

PDF, 575 KB

english, 2007

40

Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from membranes of permeabilized cells

Elsabrouty, R., Jo, Y., Dinh, T. T., DeBose-Boyd, R. A.

Journal:

Molecular Biology of the Cell

Year:

2013

Language:

english

File:

PDF, 1.24 MB

english, 2013

41

Lipid-regulated degradation of HMG-CoA reductase and Insig-1 through distinct mechanisms in insect cells

Faulkner, R. A., Nguyen, A. D., Jo, Y., DeBose-Boyd, R. A.

Journal:

The Journal of Lipid Research

Year:

2013

Language:

english

File:

PDF, 1.22 MB

english, 2013

42

Transcription Factor Hepatocyte Nuclear Factor-1 Regulates Renal Cholesterol Metabolism

Aboudehen, K., Kim, M. S., Mitsche, M., Garland, K., Anderson, N., Noureddine, L., Pontoglio, M., Patel, V., Xie, Y., DeBose-Boyd, R., Igarashi, P.

Journal:

Journal of the American Society of Nephrology

Year:

2015

Language:

english

File:

PDF, 1.42 MB

english, 2015

43

Mice infected with Schistosoma mansoni generate antibodies to LacdiNAc (GalNAc 1->4GlcNAc) determinants

Nyame, A. K., Leppanen, A. M., DeBose-Boyd, R., Cummings, R. D.

Journal:

Year:

1999

Language:

english

File:

PDF, 201 KB

english, 1999

44

Expression of Lex antigen in Schistosoma japonicum and S.haematobium and immune responses to Lex in infected animals: Lack of Lex expression in other trematodes and nematodes

Kwame Nyame, A., Debose-Boyd, R., Long, T. D., Tsang, V. C. W., Cummings, R. D.

Journal:

Year:

1998

Language:

english

File:

PDF, 387 KB

english, 1998

45

Molecular cloning and characterization of an 1,3 fucosyltransferase, CEFT-1, from Caenorhabditis elegans

DeBose-Boyd, R. A., Nyame, A. K., Cummings, R. D.

Journal:

Year:

1998

Language:

english

File:

PDF, 542 KB

english, 1998

46

Contribution of accelerated degradation to feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase and cholesterol metabolism in liver

Hwang, Seonghwan, Hartman, Isamu Z., Calhoun, Leona N., Garland, Kristina, Young, Gennipher A., Mitsche, Matthew A., McDonald, Jeffrey, Xu, Fang, Engelking, Luke, DeBose-Boyd, Russell A.

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 2.42 MB

english, 2016

47

Geranylgeranyl-regulated transport of the prenyltransferase UBIAD1 between membranes of the ER and Golgi

Schumacher, Marc M., Jun, Dong-Jae, Jo, Youngah, Seemann, Joachim, DeBose-Boyd, Russell A.

Journal:

The Journal of Lipid Research

Year:

2016

Language:

english

File:

PDF, 1.36 MB

english, 2016

48

Hypoxia-inducible factor-1α activates insig-2 transcription for degradation of HMG CoA reductase in the liver

Hwang, Seonghwan, Nguyen, Andrew D., Jo, Youngah, Engelking, Luke J., Brugarolas, James, DeBose-Boyd, Russell A.

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 9.06 MB

english, 2017

49

UbiA Prenyltransferase Domain-Containing Protein-1 Modulates HMG CoA Reductase Degradation to Coordinate Synthesis of Sterol and Nonsterol Isoprenoids

Schumacher, Marc M., Jun, Dong-Jae, Johnson, Brittany M., DeBose-Boyd, Russell A.

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 4.21 MB

english, 2017

50

Significance and regulation of lipid metabolism

DeBose-Boyd, Russell A.

Journal:

Seminars in Cell & Developmental Biology

Year:

2017

Language:

english

File:

PDF, 130 KB

english, 2017

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